Key Biologics Joins the Fight Against COVID-19

Launches new program to supply blood products from COVID-19 convalescent donors LOWELL, Mass. and MEMPHIS, Tenn. — April 29, 2020 — Key Biologics and Astarte Biologics, together the leading provider of research- and clinical-grade human immune cells, blood products, and related services to the biopharmaceutical industry, today announced the launch of an IRB-approved initiative to support […]

Useful Tools in Immunology: Catalogue of Somatic Mutations in Cancer

  The Catalogue of Somatic Mutations in Cancer (COSMIC) is the world’s largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer.  Why We Love COSMIC 1. The website is an easy, one-stop reference for all information about specific genes and mutations. 2. The cancer browser shows mutations that are […]

Research Spotlight: Nate Lavoy

Astarte’s scientists bring a wealth of immunology research expertise from diverse backgrounds. With extensive experience in a variety of biologics disciplines, our team is an ideal resource for a wide range of outsource research services. From multiplex assays to flow cytometric analyses, Astarte helps you get on with discovery. In this Researcher Spotlight, we introduce […]

Now Available: MAGE-A10 Antigen-Specific T Cells

MAGE-A10 is highly expressed in triple-negative breast cancers (Estrogen Receptor / Progesterone Receptor / HER-2-negative), an important focus for many cancer researchers. We have developed a new T cell line specific for the MAGE-A10254-263 peptide (GLYDGMEHL) and restricted by HLA-A*0201. These MAGE-A10 T cells could be the perfect complement to your cancer immunotherapy research. View […]

Ask A Scientist: What Antigens Can Stimulate IFNγ Producing CD8+ T Cells?

A curious researcher recently asked us to suggest suitable antigens that could stimulate IFNγ producing CD8+ T cells.  The short answer: Virus proteins.  But as with anything in immunology and virology, there is a longer, more complicated explanation as well.    Protein Antigens vs. Peptide Antigens CD8+ T cells normally recognize antigens that are produced […]

New: Anti-HER2/neu T Cells for Early Stage Research

What is the HER2 Antigen? HER2 is a tumor-related antigen also known as ERBB2 or NEU. The HER2 gene encodes a human epidermal growth factor receptor (EGFR) that is overexpressed by several tumor types, most notably in breast and ovarian cancers.  Many women (and men) are interested to know their HER2 status. HER2 gene amplification […]

Advantages of Mobilized Stem Cells vs. Bone Marrow Stem Cells

For decades, medical professionals and researchers have relied on and even preferred stem cells derived from bone marrow for transplantation and research purposes. When bone marrow transplantation began in 1956, this was the only way to harness the body’s most versatile cells. In the nearly 65 years since the first successful bone marrow transplant, there […]

Ask A Scientist: How Many Donors Does It Take to Cover All HLA Types?

How many donors would it take to cover all of the HLA types?  It’s a question I’ve been asked several times over the years but have struggled to answer with clarity.  HLA genes are the most diverse in the human genome. With multiple genes having hundreds if not thousands of alleles, an accurate answer to […]

Key Biologics Fills Critical Leadership Positions for High-Growth Business

Laurie Vertuccio named Director of Marketing and Rhonda Lyons named Director of Operations MEMPHIS, Tenn. and BOTHEL, Wash. — Jan. 30, 2020 — Key Biologics, the leading provider of research- and clinical-grade human immune cells, blood products, and related services to the biopharmaceutical industry, today announced it has hired two new executives to support its recent growth […]