New Resource for Antigen-Specific T Cells

Antigen-specific T cells are a powerful tool for understanding human immunity and developing treatments and cures for our most prolific diseases. Luckily, they are more readily available to researchers than ever before. Not only have we devoted many resources over the past several years to developing an exclusive inventory of antigen-specific T cells for use […]

Using Anti-MART-1 T Cells for Melanoma Immunotherapy Research

MART-1 (melanoma antigen recognized by T cells 1) is a “widely shared melanoma antigen recognized by the T lymphocytes of patients with established malignancy.” MART-1 is one of the oldest identified tumor antigens and is a protein found on normal melanocytes in the skin and retina. It is also found in most melanomas, cancers that […]

Ask A Scientist: Progenitor vs. CD34+ Cells

Progenitor cells and CD34+ cells are often referred to interchangeably as stem cells. While this oversimplification is technically correct, there are many distinctions between the origins, functions, and uses of progenitor cells and CD34+ cells. What is the Difference Between Progenitor and CD34+ Cells? Despite their many similarities, the most significant difference between the two […]

Now Available: Research-Grade Leukapheresis Products

If you missed the news in August, Astarte Biologics has merged with Key Biologics to become the leading provider of research- and clinical-grade human immune cells, blood products, and related services to the biopharmaceutical industry. As part of the merger, we are now offering leukapheresis products directly to our customers for use in late-stage immunology […]

NY-ESO-1-Specific T Cell Lines Now Available for Cancer Immunotherapy Research

After launching our first tumor-specific T cell line (anti-leukemia / WT-1 T cells) in November, we now have another exciting tumor-specific T cell line in our catalog: Anti-NY-ESO-1 T Cells! Applications for NY-ESO-1 Immunotherapies The NY-ESO-1 (New York Esophageal Squamous Cell Carcinoma 1) antigen is restricted to germ and placental cells, with re-expression in tumor […]

Our First Tumor-Specific T Cell Line: Anti-Leukemia T Cells

Our scientists are excited to announce our first true tumor-specific T cell line! Our new anti-leukemia T cells have many applications in immunotherapy research. Why an Anti-Leukemia T Cell? Our newest T cell line recognizes the WT1 tumor antigen. WT1 gets its name from a gene that was originally discovered in Wilms’ tumor, a type […]

Save Time with Ready-to-Use Mast Cells

If you use mast cells for allergy or inflammation research, you have undoubtedly wasted time procuring stem cells or bone marrow cells from a specific human or mouse donor, adding the right protein and growth factor, culturing, and incubating before finally collecting the mast cells 2–3 weeks later. All before you could even start using […]

Exploring the Functions of NK Cells in Innate and Adaptive Immunity

Natural Killer (NK) cells are the innate immune system’s first and best defense against infections. Unlike cytotoxic T cells in the adaptive immune system that require genetic matching with the target cell, NK cells are pre-programmed with cytotoxic granules that can kill any type of infected target cell. The ability to rapidly respond to an […]

The Guide to Platelet-Derived Growth Factors

Growth factors are essential to immune system research as the mechanism through which we replicate and understand cell proliferation, differentiation, and growth in vitro. There are many growth factors from which to choose for in vitro research, but selecting the right growth factor is not always a clear decision. A Focus on Platelet-Derived Growth Factors […]