Cells in Motion: Astarte Cells in 2018 Journal Articles & Patent Applications

The Astarte team is proud to support scientists around the world in pursuing their research goals, and we get excited every time a customer’s work is published.

2018 was a great year for us and our customers. Review some of the amazing journal articles and patent applications that came out over the past year using Astarte immune cells and reagents.

Congratulations to our customers on all of their hard work!  

PBMC

Antibodies that specifically bind PD-1 and methods of use. 2018.

Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release. Journal of Controlled Release. 2018.

Bispecific SCFV Immunofusion (BIF). 2018.

Modified IL-2 variants that selectively activate regulatory T cells. 2018.

Monocyte function in patients with myelodysplastic syndrome. Journal of Leukocyte Biology. 2018.

Gene array analysis of PD-1H overexpressing monocytes reveals a pro-inflammatory profile. Heliyon. 2018.

Antigen-Specific T Cells

Cancer treatment using 2-deoxy-2-fluoro-L-fucose in combination with a checkpoint inhibitor. 2018.

CUE-101, a novel Fc fusion protein for selective targeting and expansion of anti-tumor T cells for treatment of HPV-driven malignancies. 2018.

Checkpoint regulator antagonists. 2018.

Generation and analysis of human T cell lines responsive to Glatiramer Acetate. Cell Reports. 2018.

CD3+ T Cells

Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation. Scientific Reports. 2018.

Automated expansion of primary human T cells in scalable and cell‐friendly hydrogel microtubes for adoptive immunotherapy. Advanced Healthcare Materials. 2018.

An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides. Journal for ImmunoTherapy of Cancer. 2018.

Monocytes

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages. Traffic. 2018.

Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα signaling. Biochemical Journal. 2018.

BC3 T Cell Lines

Tunable Variant Immunoglobulin Superfamily Domains and Engineered Cell Therapy. 2018.

Immunomodulatory proteins with tunable affinities. 2018.

Neutrophils

Antibodies that bind peptidoglycan recognition protein 1. 2018.

Increased mortality in mice following immunoprophylaxis therapy with high 2 dosage of nicotinamide in Burkholderia persistent infections. Infection and Immunity. 2018.

Tetanus Toxoid

Anti-PD-1 antibodies and therapeutic uses thereof. 2018.

Antibodies to human programmed death receptor PD-1. 2018.

Proteoglycan Kits

Supplementation of specific carbohydrates results in enhanced deposition of chondrogenic-specific matrix during mesenchymal stem cell differentiation. Journal of Tissue Engineering and Regenerative Medicine. 2018.

Labisia pumila prevented osteoarthritis cartilage degeneration by attenuating joint inflammation and collagen breakdown in postmenopausal rat model.Inflammopharmacology. 2018.

Mast Cells

Botulinum toxin blocks mast cells and prevents rosacea like inflammation. Journal of Dermatological Science. 2018.

Lipopolysaccharides (LPS)

Converging findings from linkage between periodontal pathogen with atopic and allergic immune response. Cytokine. 2018.

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