Cells in Motion: Recent Research Using Astarte Cells

Our customers have recently published some exciting research in leading publications. Check out the latest 2019 research featuring Astarte immune cells and products. 

Effect of comedications and endotoxins on mesenchymal stem cell secretomes, migratory and immunomodulatory capacity

Durand et al. examine the effect of immunosuppressive drugs and lipopolysaccharides/endotoxins on the secretory profile, migration towards site of injury, and suppression of lymphocyte proliferation of bone marrow-derived mesenchymal stem cells.

Astarte Cells Used: PBMC

Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function

Jones et al. assess immune evasion strategies elicited by VZV that may contribute to dissemination of infection.

Astarte Cells Used: PBMC

Epstein-Barr Virus dUTPase induces neuroinflammatory mediators: Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Williams et al. aim to determine whether the EBV dUTPase protein could contribute to neuroinflammation by altering the expression of genes involved with maintaining blood–brain barrier (BBB) integrity and/or modulating synaptic plasticity.

Astarte Cells Used: Dendritic Cells

DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes

Nye et al. concluded that bacterial m6A contributes to differential gene expression and influences the ability of Group A Streptococcus to cause disease.

Astarte Cells Used: Neutrophils

Vernonia amygdalina inhibited osteoarthritis development by anti‐inflammatory and anticollagenase pathways in cartilage explant and osteoarthritis‐induced rat model

Madzuki et al. investigate the antiosteorthritis effects of VA leaf in cartilage explant assays and on postmenopausal osteoarthritis (OA) rat model. 

Astarte Cells Used: Proteoglycan Detection Kit

Epicatechin and scopoletin rich Morinda citrifolia (Noni) leaf extract supplementation, mitigated Osteoarthritis via anti‐inflammatory, anti‐oxidative, and anti‐protease pathways

Wan Osman et al. investigated the anti‐osteoarthritis effects of the MC leaf extract against joint cartilage degradation and inflammation through cartilage explant cultures and pre‐clinical animal study. 

Astarte Cells Used: Proteoglycan Detection Kit