Cells in Motion: Astarte Cells Featured in Recent Publications

Researchers have been busy using Astarte cells! Here are a few articles that were recently published in leading publications.

Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages

Velmurugan et al. explore the identification of a vacuolar compartment and the implications for understanding the subcellular trafficking process.

Astarte Cells Used:
Human Monocytes

Gene array analysis of PD-1H overexpressing monocytes reveals a pro-inflammatory profile

Bharaj et al. evaluated changes in the gene expression of monocytes after enforced PD-1H expression by gene array. They found significant alterations in candidate genes that relate to immune response, cell adhesion and metabolism.

Astarte Cells Used:
PBMC

Monocyte function in patients with myelodysplastic syndrome

Findings from a recent study by Pollyea et al. suggest that monocytes could compensate for other immune deficits in patients with myelodysplastic syndrome (MDS), a malignant hematopoietic stem cell disorder that frequently evolves into acute myeloid leukemia (AML).

Astarte Cells Used:
PBMC

An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides

Eggink et al. found that the peptide sv6D is a functional ligand for CLEC10A and induces maturation of immune cells in the peritoneal cavity. Read more about the study.

Astarte Cells Used:
CD3+ T Cells

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