Ask A Scientist: How Many Donors Does It Take to Cover All HLA Types?

How many donors would it take to cover all of the HLA types?  It’s a question I’ve been asked several times over the years but have struggled to answer with clarity.  HLA genes are the most diverse in the human genome. With multiple genes having hundreds if not thousands of alleles, an accurate answer to […]

Key Biologics Fills Critical Leadership Positions for High-Growth Business

Laurie Vertuccio named Director of Marketing and Rhonda Lyons named Director of Operations MEMPHIS, Tenn. and BOTHEL, Wash. — Jan. 30, 2020 — Key Biologics, the leading provider of research- and clinical-grade human immune cells, blood products, and related services to the biopharmaceutical industry, today announced it has hired two new executives to support its recent growth […]

Phacilitate 2020: A Focus on Patient Voices

Phacilitate 2020 was jam-packed with inspiration, motivation, and confirmation that what we are doing is making an impact on patient lives now and into the future. We attended several educational sessions, met with many scientists, and had countless conversations about the future of immunotherapy. Here are some of our top Phacilitate 2020 highlights.   2020 […]

Breaking from AACR: Profiling the TCR Beta Repertoire in NSCLC Donors

TCRβ sequencing is currently being explored in oncology research as a potential predictor for patient response to immunotherapies.   Researchers from Biodesix, Inc. shared their most recent findings in this area at the AACR Advances in Liquid Biopsies conference in Miami from January 13–16, 2020. The research, co-authored by Astarte’s Benjamin Tjoa, evaluated peripheral blood lymphocytes […]

Using PBMC as a Quality Control for Flow Cytometry

Our cryopreserved peripheral blood mononuclear cells are a great tool for flow cytometry assays. Whether you want to confirm your antibodies are working properly or measure for consistency, our PBMC are the tools you need for quality control.  Using PBMC to Test Antibodies Sometimes you might not be sure if your chosen reagent is correctly […]

Ask A Scientist: How Do I Use Dendritic Cells for an MLR?

Our resident dendritic cell expert, Benjamin Tjoa, was one of the first scientists in the world to develop dendritic cells for use in cell-based vaccines. Ben has traveled internationally to help labs prepare for developing dendritic cell-based therapies. Monocyte-derived dendritic cells are a hot topic for many of our customers, and Ben has answered countless […]

Useful Tools in Immunology: The Human Protein Atlas

When I need more information on a protein or antibody, one of the first places I turn to is The Human Protein Atlas. It’s a remarkable open-access collection of all known proteins in human cells, tissues, and organs.  When I say remarkable, I mean it. The Human Protein Atlas has amassed detailed information on more […]

In-Depth Guide for Working with Macrophages

Macrophages have many applications in immunology research and can produce a wide range of cytokines and chemokines that can influence the immune response in both mouse and human models.  We’ve compiled an in-depth guide with our best resources for working with macrophages, the “Big Eaters” of the immune system. You’ll get tips for creating and […]

How to Differentiate Monocytes into Osteoclasts

Our contract immunology research team is always looking for a new challenge. So when a customer proposed a project that involved differentiating monocytes into osteoclasts, we said, “Why not!” Fun in the Lab with Monocytes Osteoclasts are macrophages found in bone and are highly specialized myeloid cells that break down and resorb bone tissue, important […]