Immunology for Non-Immunologists: Proliferation Assays

What are Proliferation Assays? Proliferation assays are a category of immune cell activation tests designed to measure cell division. Proliferation assays are some of the most commonly used measures of immune cell activation. Examples include: Tritiated Thymidine Incorporation (3H-thymidine Incorporation) Bromodeoxyuridine Incorporation (BrdU) Tetrazolium Dyes CFSE Dye Reduction CellTiter-Glo® Learn more about each method below. […]

Researcher Spotlight: Chris Tompkins

Astarte’s scientists bring a wealth of immunology research expertise from diverse backgrounds. With extensive experience in a variety of biologics disciplines, our team is an ideal resource for a wide range of outsource research services. From multiplex assays to flow cytometric analyses, Astarte helps you get on with discovery. In this researcher spotlight, we introduce […]

NY-ESO-1-Specific T Cell Lines Now Available for Cancer Immunotherapy Research

After launching our first tumor-specific T cell line (anti-leukemia / WT-1 T cells) in November, we now have another exciting tumor-specific T cell line in our catalog: Anti-NY-ESO-1 T Cells! Applications for NY-ESO-1 Immunotherapies The NY-ESO-1 (New York Esophageal Squamous Cell Carcinoma 1) antigen is restricted to germ and placental cells, with re-expression in tumor […]

Ask A Scientist: How to Thaw, Handle & Store Frozen Cells

Thawing frozen immune cell products can be tricky if you don’t take the proper precautions. It’s best to be well versed in thawing, handling and storage techniques before receiving your cells so you can ensure viability and function for your research. Many customers have similar cell handling questions, so we’ve compiled some of the most […]

Useful Tools in Immunology: The Immune Epitope Database

The Immune Epitope Database (IEDB) is a free online resource established by the National Institute for Health. The IEDB makes it easy for scientists and researchers to search for experimental data characterizing antibody and T cell epitopes for allergens, infectious diseases, autoimmune diseases, and transplants/alloantigens. Beyond epitope search, the IEDB also offers unique epitope analysis […]

Comparison of Culture Media for In Vitro T Cell Expansion and Function: SITC 2018 Research

Our team recently presented our findings on the effect of culture medium and supplementation on T cell proliferation and function at SITC 2018. The research was well-received, and we thank each of you who stopped by to ask questions. If you weren’t at SITC or missed our presentation, the full abstract and poster are below. […]

Our First Tumor-Specific T Cell Line: Anti-Leukemia T Cells

Our scientists are excited to announce our first true tumor-specific T cell line! Our new anti-leukemia T cells have many applications in immunotherapy research. Why an Anti-Leukemia T Cell? Our newest T cell line recognizes the WT1 tumor antigen. WT1 gets its name from a gene that was originally discovered in Wilms’ tumor, a type […]

Immunology for Non-Immunologists: Challenges and Opportunities with Influenza Virus

Influenza is a complex, unpredictable virus that has kept scientists searching for more universal vaccinations and treatments to the deadly disease. Two mechanisms render the immune system ineffective in fighting the influenza virus: antigenic drift and antigenic shift. Antigenic Drift: Due to the lack of RNA proofreading enzymes, influenza virus genomes can accumulate mutations through […]